The future of antibiotic development: Combating resistance with innovation

Abstract

Antibiotic resistance is a critical global health threat, driven by the overuse of antibiotics and the slow development of new treatments. This mini-review highlights innovative strategies for combating antimicrobial resistance, including the use of artificial intelligence, CRISPR-based therapies, antimicrobial peptides, and phage therapy. It also addresses economic and regulatory challenges hindering antibiotic innovation and emphasizes the importance of global collaboration and stewardship programs. Novel technologies and multidisciplinary approaches hold promise for revitalizing antibiotic development, ensuring effective treatments for future generations.